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Y-39983 HCl - CAS# 173897-44-4 0217 Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C

Y-39983 HCl - CAS# 173897-44-4 0217 Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C

Name: Y-39983 HCl - CAS# 173897-44-4 0217 Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C
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SKU: 90410899807
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SKU: 90410899807

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Y-39983 HCl - CAS# 173897-44-4 0217 Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)CY 39983 HCl, CAS No. 173897 44 4, also known as Y 33075, is a potent and selective inhibitor of ROCK family with IC50 value of 3. 6nM for ROCK. Y 39983 attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination. Y 39983 downregulates RhoA Rho associated kinase expression during its promotion of axonal regeneration. Y 39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats.

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Description

Smiles: CN(C)C1C=CC(=CC=1)C(C1=CC(=CC=C1Cl)[N+]([O-])=O)C1C=CC(=CC=1)N(C)C

InChi: InChI=1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8

InChiKey: IHLVSLOZUHKNMQ-UHFFFAOYSA-N

936890-98-1

It also binds to D4 (pKi = 7

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